When WT EO771 or Xkr8 KO cells were injected into NSG mice, which have a dysfunctional adaptive immune system, the KO tumors grew at a similar rate compared to the EO771 WT tumors, as shown by relative tumor volume, compared to WT at endpoint (Fig. 2E) and tumor weight (Fig. 2F). This evidence concerns the gene XKR8 and neoplasm.