XKR8 and cancer: Furthermore, EO771 cells express the two main PS scramblase isoforms Xkr8 (caspase-activated) and TMEM16F (stress and calcium-activated), permitting molecular dissociation of the cancer cell-intrinsic events, side-by-side, associated with apoptosis/efferocytosis (Xkr8) from the events associated with calcium dysregulation and PS externalization on oncogenic viable cells (TMEM16F).