Monocyte recruitment to inflamed tissue is orchestrated by chemokines, CCL2, CCL7, and CCL20, which are upregulated in response to proinflammatory stimuli, as well as by cytokines such as IFN-γ and TNF-α, both of which are elevated in the granulomatous microenvironment.75, 76Monocytes in sarcoidosis demonstrate enhanced migratory potential, shaped by dynamic regulation of chemokine receptors across compartments. This evidence concerns the gene IFNG and sarcoidosis.