In addition, clinical factors were prone to be AAV-ILD, including having positive MPO-ANCA, lower ESR, higher KL-6, higher Hb, moderate and high BVAS, fever, Ear, nose & throat, dyspnea, cough, alb, and HRCT findings such as honeycombing, interlobular septal thickening, and lattice shadows. This evidence concerns the gene MPO and interstitial lung disease.