However the study conducted on e-biopsy samples from cutaneous SCC and BCC lesions revealed overexpression of cornulin (CRNN), estrogen sulfotransferase (SULT1E1), and inositol-tetrakisphosphate 1-kinase (ITPK1) in BCC, compared SCC [35]. The gene discussed is ITPK1; the disease is skin basal cell carcinoma.