Mutations in the Hedgehog pathway, tumor protein p53 (TP53), the RAS (GTPase) gene family in cutaneous BCC and CDKN2A (Cyclin-dependent kinase inhibitor 2A), TP53, H-RAS in cutaneous SCC as well as TP53, NRAS and BRAF proto-oncogenes in melanoma draw attention in the context of altered energy metabolism [65,66]. This evidence concerns the gene TP53 and skin basal cell carcinoma.