No significant differences were observed in bodymass index, age at hypertension onset, defined daily doses of antihypertensives,family history of hypertension or early cardiovascular disease, mean arterialpressure, preoperative levels of aldosterone, renin, potassium, creatinine, orelectrocardiogram changes, nodule size, or postoperative levels of antihypertensivesand creatinine. This evidence concerns the gene REN and hypertensive disorder.