NPPB and acute kidney injury: Of the included studies,nine[3,22,23,28,34,43,50,54,58] demonstrated a significant association between NT-proBNPlevels and the development of postoperative AKI in univariate analysis.Belley-Côté et al.[45] (2016) in their prospective cohort also showed anindependent association between high pre-surgical levels of NT-proBNP and severe AKI(P = 0.030), which similarly occurred in the studies byVerwijmeren et al.[57](2021) e Wang et al.[59] (2021).