Notably, the cutC gene (55), responsible for choline-to-TMA conversion, was detected in A. hadrus MAGs from both CAD and control groups, whereas the cntA/yeaW gene (56, 57), associated with TMA production from ammonium compounds like carnitine and γ-butyrobetaine, was present in M. fumiformis MAGs from both CAD and control groups. The gene discussed is CUTC; the disease is coronary artery disorder.