NDRG1 and colorectal carcinoma: Functional validation using CRC organoids and mouse models demonstrates that the one‐carbon metabolism enzyme SHMT1 promotes CRC tumorigenesis and metastasis via formate‐mediated AMPK inhibition, whereas PIM kinase‐dependent NDRG1 Ser330 phosphorylation exacerbates liver metastasis by promoting ubiquitin‐dependent degradation of NDRG1.