Resveratrol, a polyphenol found mainly in plant sources such as grapes, blueberries, apple, carrot, peanuts etc. enhance the anti-proliferative effects of chemotherapeutic agents bestatin in chronic myelogenous leukaemia (CML) by decreasing the function and expression of p-glycoprotein (P-gP). The gene discussed is PGP; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.