In contrast, the addition of B 1,000 nM resulted in a significant reduction of the proportion of pSTAT3-expressing cells in CD4+T cells (8.2% ± 2.5%), CD8+ T cells (6.8% ± 2.0%), and CD11b+ cells (0.3% ± 0.1%) in SLE (Figures 3B, D, F). Here, ITGAM is linked to systemic lupus erythematosus.