GPT and Acute hepatic failure: Moreover, in reports of dogs with acute hepatic failure from xylitol intoxication, the degree of elevation of bilirubin, ALT, and AST was more profound than in this dog (bilirubin 17.1–85.5 μmol/L [1.0–5.0 mg/dL], ALT 1000 to > 10,000 U/L and AST 3251 to > 25,000 U/L) [14, 17].