The tumor‐infiltrating CD8+ T cells were obtained and classified into three broad cell groups[18]: the non‐exhausted cell subset (CD8‐C1‐non‐exhausted), the terminal exhausted cell subset (CD8‐C2‐Texterm), and the proliferative cell subset (CD8‐C3‐prolif) (Figure1A). This evidence concerns the gene CD8A and neoplasm.