Through Spearman correlation analysis of GSPT1 with tumor mutation burden (TMB) and microsatellite instability in pan‐cancer (Figure 7D,E), we found that GSPT1 is significantly positively associated with the TMB of SARC, STAD, PAAD, and LAML and the microsatellite instability of ACC, UCS, TGCT, READ, lung squamous cell carcinoma, LIHC, LAML, KIRC, KICH, and GBM. Here, GSPT1 is linked to cancer.