For instance, proteomic analysis of symptomatic carotid plaques revealed specific molecular signatures that could serve as biomarkers for atherosclerosis, such as MMP9, cathepsin D, and galectin‐3‐binding protein.[379] Similarly, the proteomic signature of human plasma can be used to study how different organs are aging and whether organ‐specific accelerated aging confers increased risk for the development of organ‐specific diseases.[380] Epigenomic analyses instead can allow for the identification of epigenetic modifications that are linked with vascular function and aging. This evidence concerns the gene CTSD and atherosclerosis.