CSF3 and leukemia: Administration of ISO after G-CSF mobilization was found to increase the number of favorable cells—likely to induce graft-versus-leukemia (GvL) effects, such as NK and γδ T cells—while decreasing the number of unfavorable cells—likely to provoke GvHD, such as B cells—per CD34 + cell count (Fig. 1K-O).