We then expanded the analysis of the cGAS-STING target gene expression in AML harboring either conformational or contact p53 mutants, and confirmed that AML harboring contact p53 mutants show the highest expression of cGAS-STING target genes compared to those harboring conformational mutp53 or WT-p53 (Fig. S9B). The gene discussed is TP53; the disease is acute myeloid leukemia.