For example, IFIX is a DNA sensor that has anti-viral and anti-tumor activities (DeYoung et al, 1997; Diner et al, 2015; Ding et al, 2004), and MNDA regulates the transcription of IRF7 by recruiting RNA polymerase II to its promoter (Gu et al, 2022). Here, MNDA is linked to neoplasm.