PML and viral infectious disease: Nonetheless, multiple previous data and the data in this study (Supplementary Fig. 4) support the biological relevance of our findings, including alignment of our observations of P3-LLPS-associated phenotypes with data from infection-based assays on interactions (i.e., P protein NB formation (Supplementary Fig. 4), MT bundling26, effects of infection on PML NBs24) and functional roles of identified P1/P3 interactors during viral infection (e.g., NCL23, RPL949, Staufen-152).