Dysfunction of TBK1 is linked to a number of human diseases, most prominently (ALS) and ALS/frontotemporal dementia (ALS/FTD), but also herpes simplex encephalitis (HSE), diabetes, obesity, cancer, and normal tension glaucoma (NTG) (Ahmad et al., 2016). The gene discussed is TBK1; the disease is amyotrophic lateral sclerosis.