Therefore, next to the non-adjusted data (Fig. 2B and D), we plotted the levels of glutamate, LDH, and NfL relative to the viral load at 10dpi based on the TCID50 for lab adapted strains of HPeV-1 and HPeV-3 respectively [6], to emphasize the potency of HPeV-1 and HPeV-3 to alter host mechanisms upon infection(Fig. 2C, E, G). This evidence concerns the gene NEFL and infection.