IL5 and Increased total eosinophil count: Despite the enrichment of eosinophils in the lung at 7 days post-challenge (DPC), no significant IL-5 or Eotaxin-1 (CCL11) signature was observed in lung homogenate supernatant cytokine/chemokine analysis, in contrast to observations in OVA-sensitized, allergic, positive control mice with robust eosinophilia, which exhibited high concentrations of IL-5 and CCL11 (24).