For further investigation, we detected the expression of CPNE3 in NSCLC cell lines and found that the expression of CPNE3 in lung cancer cell lines (HCC827, PC‐9, H1299, A549, H1650, H460, H1703, H226 and H520) was higher than that in a normal lung epithelial cell line (BEAS‐2B) using western blotting and qRT–PCR (Figure 1J). This evidence concerns the gene CPNE3 and non-small cell lung carcinoma.