Like women with PCOS, the SAT of the PCOS-like sheep is dysfunctional, with larger adipocytes, decreased adiponectin, more inflammatory markers and IR (Ramaswamy et al. 2016, Siemienowicz et al. 2020, Siemienowicz et al. 2021, Levate et al. 2024). This evidence concerns the gene ADIPOQ and polycystic ovary syndrome.