IL2 and inflammatory bowel disease: This modification, as it seems, may be of different nature in different study groups and undoubtedly depends on many factors including the age of the patients, the state of their immune system, comorbidities, antigenic stimulation, etc. The results on the effect of L. rhamnosus on the concentration of IL‐2 also vary in different groups, and so, for example, in patients with inflammatory bowel diseases under the influence of probiotics, the concentration of IL‐2 decreases while in patients with systemic lupus an increase in the concentration of this cytokine is observed.