The protective effect against infections in our patients, whose IL‐2 concentrations were relatively high, may be related to the stimulation of the production of stimulated growth and differentiation of T lymphocytes, the stimulation of their production of IFN gamma, and the effect of IFN gamma and IL‐2 on the one hand on cell‐type responses such as cytotoxic T lymphocytes or NK cells on the other hand on the production of IgG and IgM antibodies by B lymphocytes (You et al. 2014; Braat et al. 2004; Alaei et al. 2023; Jounai et al. 2012; Guo et al. 2022; Arenas‐Ramirez et al. 2015). This evidence concerns the gene CD40LG and infection.