Further, we used online tool TISCH2 (http://tisch.compbio.cn/home) (Accessed date: 2 June 2025) and attached single-cell datasets of prostate cancer (GSE_137829, GSE_141445, GSE_172301 and GSE_176031) to detect HSPB8 distribution within the prostate gland. This evidence concerns the gene HSPB8 and Familial prostate cancer.