Considering the relatively slight differences in HSPBP1 and HSPA13 expression between normal prostatic tissues and prostate cancer tissues shown in the online tool GEPIA (http://gepia.cancer-pku.cn/) (Accessed date: 16 May 2025), HSPB8 was considered to be the gene of interest for further analysis. Here, HSPB8 is linked to Familial prostate cancer.