STEMI: ST-elevation myocardial infarction, PCI: percutaneous coronary intervention, MPO: myeloperoxidase, OCT: optical coherence tomography, MBG: myocardial blush grade, TIMI: thrombolysis in myocardial infarction, IV: intravenous, MI: myocardial infarction, EVs: extracellular vesicles, AMI: acute myocardial infarction, ACS: acute coronary syndrome, GG: genotype-guided group, SG: standard (control) group, HTPR: high on-treatment platelet reactivity, RCT: randomized controlled trial. This evidence concerns the gene MPO and ST Elevation Myocardial Infarction.