CDKN1A and inflammatory response: Genes involved in cell cycle, inflammation, and phagocytic function included Ccnd2, Cdkn1a, Cdkn1b, Nlrp6, Il4ra, Il5ra, Il33, Cd36, C3, et al. (Figure 1E), which regulate NSC proliferation, neurogenesis, and microglia-mediated hippocampal inflammation (23–27).