Our study identified TyG-BMI, height, albumin (ALB), body mass index (BMI), albumin/globulin ratio (A/G), alanine aminotransferase (ALT), systolic blood pressure (SBP), and diabetes as risk factors for MAFLD in the elderly, while high-density lipoprotein cholesterol (HDL-C) served as a protective factor. This evidence concerns the gene GPT and diabetes mellitus.