Using the GEO2R tool, the analysis of microarray gene expression data of the GSE48350 dataset demonstrated that the expression of four genes [RTF1 homolog, Paf1/RNA polymerase II complex component (23168, RTF1), long intergenic non-protein coding RNA 3007 (646588, LOC646588/LINC03007), long intergenic non-protein coding RNA 2987 (101927151, LOC101927151/LINC02987), and ribonucleic acid export 1 (8480, RAE1)] was downregulated in the HC of male AD patients (n = 9, age range: 76-94 years) compared to male controls (n = 10, age range: 75-97 years) (Data Appendix B, Data S24). Here, RTF1 is linked to Alzheimer disease.