A study of whole-exome sequencing identified mutations of charged multivesicular body protein 2B (CHMP2B), SQSTM1, PARK2, eukaryotic translation initiation factor 4 gamma 1 (EIF4G1), and GRB10 interacting GYF protein 2 (GIGYF2) in patients with sporadic DLB [189]. The gene discussed is CHMP2B; the disease is Lewy body dementia.