MAP3K5 and dopaminergic neuroblastoma: Apoptosis signal-regulating kinase 1 (ASK1, also known as MAP3K5) induces apoptosis through the activation of p38 MAPK and JNK in human SH-SY5Y dopaminergic neuroblastoma cells exposed to 6-hydroxydopamine (6-OHDA) [318] (Figure 9E).