Immunohistochemical stains with antibodies directed against CD3, CD5 (T-cell), CD20 (B-cell), CD79, Ki67 (proliferation index – tumor aggressiveness), kappa and lambda light chains, immunophenotyping, molecular genetic studies, and flow-citometry provide additional information for accurate subtyping [1,7,13,16,19]. The gene discussed is MKI67; the disease is neoplasm.