DYRK1A and Dravet syndrome: This genetic alteration leads to DYRK1A overexpression (Lowe et al., 2019; Wegiel et al., 2008), disrupting neurogenesis and gliogenesis during brain development, which contributes to the neurological impairments exhibited by DS individuals (Guedj et al., 2012; Stagni and Bartesaghi, 2022).