Moreover, allicin enhances insulin production and pancreatic β-cell function by upregulating the AMP-activated protein kinase/mammalian target of rapamycin-mediated autophagy pathway and inhibits advanced glycation end products by upregulating of antioxidant defense system in the STZ-induced T1DM models (47, 48). The gene discussed is MTOR; the disease is type 1 diabetes mellitus.