MYC and cancer: Key findings include: (1) While GIM incidence increases with age, the histological severity within a single biopsy does not show a corresponding age-dependent increase; (2) Severe GIM is strongly associated with the Type III (incomplete colonic) subtype; (3) c-Myc expression correlates negatively with advancing GIM subtype (Type I to Type III), despite Type III carrying higher cancer risk, suggesting potential post-translational regulation.