Notably, OM was linked to increased levels of interleukin-15 receptor α (IL15RA; odds ratio [OR] = 1.077, 95% CI: 1.046–1.108, P < .001), C-X-C motif chemokine ligand 1 (CXCL1; OR = 1.054, 95% CI: 1.028–1.081, P < .001), fms-related tyrosine kinase 3 ligand (FLT3LG; OR = 1.054, 95% CI: 1.027–1.081, P < .001), interleukin-20 (IL20; OR = 1.053, 95% CI: 1.023–1.082, P < .001), and IL10 (OR = 1.047, 95% CI: 1.017–1.077, P = .002). The gene discussed is CXCL1; the disease is ocular melanoma.