CD8A and Parkinson disease: Ginsenosides, identified as triterpene glycosides and extracted from ginseng, with over 500 variants recognized, play a significant role in PD treatment.[165] Specifically, ginsenoside Rg1 in MPTP PD models boosts CD3 and CD4 T cell levels in peripheral blood, lessens CD3 and CD8 T cell levels, and reduces the infiltration of CD3 T cells in the SNpc region.