Eight myelodysplasia-associated somatic variants in the BCOR/BCORL1, DNMT3A, ASXL1, CUX1, and ETV6 genes were found in 7 patients (5 AA and 2 MDS-h patients, 17%); neither AA patient had evidence of myelodysplasia at the time of analysis. The gene discussed is ASXL1; the disease is myelodysplastic syndrome.