Parameter estimation relies on three tumor volume measurements obtained over a 14-day period in a genetically engineered pancreatic cancer model (\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$${{Kras}}^{{\rm{LSL}}-{\rm{G12D}}}\,;\,{{Trp53}}^{{\rm{LSL}}-{\rm{R172H}}}\,;\,{Pdx1}-{\rm{Cre}}$$\end{document}KrasLSL-G12D;Trp53LSL-R172H;Pdx1-Cre). The gene discussed is PDX1; the disease is familial pancreatic carcinoma.