LINC02449 and Behcet disease: Given that BD-associated upregulation of LINC02449 expression was observed in the cortex in the PsychENCODE dataset (Supplementary Data 2)37 and that LINC02449 is highly expressed in the human cortex according to the GTEx dataset (Supplementary Fig. S2)41, we injected rAAV into the medial prefrontal cortex (mPFC) region of 8-week-old male C57BL/6 mice (Fig. 2A).