The FA SCC clinical data similarly showed a statistically significant decrease in expression in key lysosomal and lysosomal exocytosis related genes: TFEB and mucolipin 1 (MCOLN1) in FA SCC patient samples compared to sporadic HNSCCs (−1.71 log2 fold change (p-value < 2.01 e −9) and −2 log2 fold change (p-value < 8.46 e−19), respectively) [58]. This evidence concerns the gene MCOLN1 and Friedreich ataxia.