The miRNA‐181 family exhibits dual regulatory roles in oncogenesis, functioning as both tumor‐promoting and tumor‐suppressing microRNAs through the modulation of multiple signaling pathways, particularly the PI3K/AKT, MAPK, TGF‐β, Wnt, NF‐κB, and Notch cascades [43]. This evidence concerns the gene AKT1 and neoplasm.