We selected and then evaluated three upregulated genes (HNRNPC, PLK1, and RCC1) and two downregulated genes (PRC1, UBA52) that were among the core genes associated with PCa, along with their upstream miRNAs, including miR-124-3p, miR-133a-3p, and miR-17-5p. Here, UBA52 is linked to posterior cortical atrophy.