KLK3 and posterior cortical atrophy: Overall, 2016 to 2022 AAPC for 2- to 5-year prediagnosis PSA testing was −0.29% (95% CI, −0.31% to −0.26%) for localized PCa and −0.67% (95% CI, −0.73% to −0.60%) for late-stage PCa (Table).