HNRNPU and hepatocellular carcinoma: In addition, ZBTB7A is a transcription factor of RP11386G11.10.HNRNPU promotes the expression of ZBTB7A in HCC cells, thereby increasing the transcriptional activity of RP11386G11.10 and forming a positive feedback loop, which ultimately leads to continuous lipid accumulation, growth and metastasis in HCC cells [86].