A series of follow-­up studies have shown that SNHG4 promoted the progression and malignancy of HCC through upregulating CREB5 via sponging miR­211­5p.the above findings suggest that SNHG4 promotes HCC malignancy through the SNHG4/miR­211­5p/CREB5 axis [47]. Here, CREB5 is linked to hepatocellular carcinoma.