For instance, targeting the AHR has also been proposedfor the treatment of cancer, as wellas for treating certain inflammatory skin conditions, such as dermatitisand psoriasis,, and inflammatory gut conditions,including Crohn’s disease. Thenatural compound and AHR agonist tapinarof has been approved as atopical treatment for plaque psoriasis. The gene discussed is AHR; the disease is psoriasis vulgaris.