TRIB3 and atherosclerosis: Second, our murine atherosclerosis data suggest a key role for the suppression of macrophage-TRIB3 in enhancing efferocytosis and promoting plaque stability; however, it is possible that some of the observed effects may also arise from loss of TRIB3 signaling in nonmacrophage leukocytes, such as T and B cells, which, although expressing only low levels of TRIB3, could still contribute.