ATF1 and tumor of salivary gland: The negativity for smooth muscle actin aids in ruling out the myoepithelial origin [5]. Recent studies have consistently identified the Ewing sarcoma breakpoint region 1-activating transcription factor 1 (EWSR1-ATF1) fusion gene in HCCC, while EWSR1 rearrangements have not been detected in other salivary gland tumours, highlighting the specificity of this genetic alteration to HCCC [7].