Anti-N-methyl-D-aspartate receptor encephalitis (NMDAR-E) is an autoimmune disorder characterized by IgG antibodies against the GluN1 subunit of the NMDA receptor in cerebrospinal fluid (CSF), leading to a wide range of neuropsychiatric symptoms, including acute psychosis, seizures, movement disorders, and cognitive impairment [1,2]. This evidence concerns the gene GRIN1 and autoimmune disease.