Laboratory investigations revealed leukocytosis (WBC: 22 x 109/L), hyperbilirubinemia (total bilirubin: 74 μmol/L, direct bilirubin: 55 μmol/L), and elevated liver enzymes (alkaline phosphatase (ALP): 128 U/L; aspartate aminotransferase (AST): 344 U/L; alanine aminotransferase (ALT): 344 U/L; gamma-glutamyl transferase (GGT): 720 U/L). The gene discussed is GPT; the disease is Increased total leukocyte count.