Liu et al. screened 1,921 patients with PD for GBA1 mutations and found that carriers of neuropathic Gaucher disease mutations and complex GBA1 alleles exhibited a more rapid decline in Mini-Mental State Examination (MMSE) scores, whereas this association was not observed in carriers of non-neuropathic mutations or risk variants [114]. The gene discussed is GBA1; the disease is Parkinson disease.