Also, mVenus-p27K−-positive E0771 mouse breast cancer cells and B16 melanoma cells isolated from co-cultures with MLECs started to proliferate in vitro when cultured alone (Fig. 1L and M) and showed primary tumor growth in vivo (Fig. 1N and O) suggesting that dormant tumor cells can be reactivated. This evidence concerns the gene PSMA6 and melanoma.